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Acupuncture has been found to have a beneficial effect on the symptoms
and hormone secretion of menopausal women.
Philp
HA Hot flashes - a review of the literature on alternative
and complementary treatment approaches. Altern Med Rev
2003 Aug;8(3):284-302. "Hot flashes are a common experience
for menopausal women, with an 85-percent incidence in the West.
With the increased knowledge of side effects attributable to conventional
treatment options, more women are exploring natural alternatives.
Although more definitive research is necessary, several natural
therapies show promise in treating hot flashes without the risks
associated with conventional therapies. Soy and other phytoestrogens,
black cohosh, evening primrose oil, vitamin E, the bioflavonoid
hesperidin with vitamin C, ferulic acid, acupuncture treatment,
and regular aerobic exercise have been shown effective in treating
hot flashes in menopausal women."
Porzio
G, Trapasso T, Martelli S, Sallusti E, Piccone C, Mattei A, Di Stanislao
C, Ficorella C, Marchetti P. Acupuncture in the treatment
of menopause-related symptoms in women taking tamoxifen.
Tumori. 2002 Mar-Apr;88(2):128-30. "Fifteen patients were enrolled
in a pilot study to evaluate the safety and efficacy of acupuncture
for the treatment of menopausal symptoms in tamoxifen-treated patients.
Patients were evaluated before treatment and after one, three and
six months with the Greene Menopause Index and were treated according
to the traditional Chinese medicine. Anxiety, depression, somatic
and vasomotor symptoms were improved by the treatment; libido was
not modified. Acupuncture seems to be safe and effective for the
treatment of menopausal symptoms in women with previous breast cancer
taking tamoxifen. Confirmatory studies with a larger number of patients
and with a placebo-treated group are warranted."
Dong
H, Ludicke F, Comte I, Campana A, Graff P, Bischof P.
An exploratory
pilot study of acupuncture on the quality of life and reproductive
hormone secretion in menopausal women. J Altern Complement
Med. 2001 Dec;7(6):651-8. "The majority of menopausal women
suffer from climacteric symptoms. The purpose of this study was
to assess the effects of acupuncture on the quality of life and
reproductive hormones secretion in menopausal women. Eleven (11)
menopausal women with climacteric symptoms entered this prospective
study. The Menopause Specific Quality of life Questionnaire was
filled out by the patients before the first acupuncture session,
after the last one (5 weeks later), and 3 months after the last
acupuncture session. Reproductive hormones including follicular-stimulating
hormone (FSH), luteinizing hormone (LH), estradiol, progesterone,
and prolactin were measured before and after treatment. Acupuncture
significantly improved menopausal vasomotor symptoms (p = 0.001
and p = 0.003 for the end of treatment and 3 months later, respectively)
and physical symptoms (p = 0.014 at the end of treatment and p =
0.046 3 months later). It did not change psychosocial or sexual
symptoms, nor did it change the measured reproductive hormones.
In conclusion, acupuncture is shown to be effective in relieving
vasomotor and physical disturbances of menopausal women with effects
lasting at least up to 3 months after termination of the treatment.
Acupuncture may be a useful treatment alternative for women who
are unable or do not want to receive hormone replacement therapy.
A prospective study with larger sample sizes will be needed to define
the role of acupuncture in the management of menopausal symptoms."
Sandberg
M, Wijma K, Wyon Y, Nedstrand E, Hammar M. Effects of
electro-acupuncture on psychological distress in postmenopausal
women.Complement Ther Med. 2002 Sep;10(3):161-9. "OBJECTIVES:
To evaluate effects of electro-acupuncture (EA) on general psychological
distress and relate to experience of climacteric symptoms in 30
postmenopausal women. DESIGN: A randomised single-blind controlled
design was used to evaluate effects of EA and extremely superficial
needle insertion, with the latter serving as a near-placebo control.
SETTINGS: The Linkoping University Hospital in Sweden. Interventions:
Fourteen treatments during 12 weeks with follow-ups at 3 and 6 months.
OUTCOME MEASURES: General psychological well-being, mood and experience
of climacteric symptoms. RESULTS: Mood Scale improved only in EA
group and not until 12 weeks compared to baseline, from 110 to 129
(P = 0.01), and to 120 at 3-month follow-up (P = 0.04). Mood was
significantly better than control at 8 (P = 0.05) and 12 weeks (P
= 0.01). Visual analogue scale estimation of climacteric symptoms
was decreased at 4 weeks in both groups, and lasted throughout the
study period, in EA group from 5 to 2 (P = 0.04) and in control
group from 5 to 3 (P = 0.02) at 6-month follow-up. Well-being was
ameliorated from 4 weeks in EA and from 8 weeks in control group
until end of study (P = 0.01, P = 0.03). No significant differences
on climacteric symptoms or well-being existed between the groups.
CONCLUSIONS: This study does not show that EA is better than superficial
needle insertion for the amelioration of general psychological distress
and experience of climacteric symptoms in women with vasomotor symptoms
after menopause. However, the more pronounced effect on mood suggests
that EA might have additional effects compared with superficial
needle insertion."
Wyon
Y, Lindgren R, Hammar M, Lundeberg T. Acupuncture against
climacteric disorders? Lower number of symptoms after menopause.
[Article in Swedish] Lakartidningen. 1994 Jun 8;91(23):2318-22.
"Vasomotor symptoms are very common among perimenopausal women,
but also among orchidectomized men. The cause of the symptoms is
not the low steroid concentrations per se, but probably changes
in central neuropeptide activity. Twenty-four healthy women with
natural menopause, suffering from hot flushes, were included in
the study and randomly assigned to either of two groups, one group
received treatment with electrostimulated acupuncture (EA), the
other with superficial needle position (SNP) acupuncture. Treatment
was given for totally of eight weeks, twice a week during the first
two weeks, and then once a week for the remaining six weeks. As
recorded in logbooks kept by the participants, the frequency of
flushes decreased significantly by more than 50 per cent in both
groups, and remained decreased in the EA group, whereas in the SNP
group it increased slightly again over the three months after treatment.
Values for the Kupperman Index decreased in both groups during treatment,
changes still evident at three-month follow-up, whereas the self-rated
general climacteric symptoms (VAS) decreased significantly in the
EA group only. The PGWB (Psychological General Well-Being) index
did not change significantly in either group during treatment."
Toriizuka
K, Okumura M, Iijima K, Haruyama K, Cyong JC. Acupuncture
inhibits the decrease in brain catecholamine contents and the impairment
of passive avoidance task in ovariectomized mice. Acupunct
Electrother Res. 1999;24(1):45-57. "The effects of acupuncture
on the disorders elicited by abnormalities of endocrine system were
investigated in ovariectomized mice. Female mice (strain; C57BL/6)
were ovariectomized (OVX) and acupuncture points, Shenshu ([Japanese
pictograph see text] : BL23) on both side of the back were continuously
stimulated by subcutaneous needles for 20 days. After completion
of experimental sessions, animals were sacrificed and specific brain
regions were assayed for catecholamine contents by high performance
liquid chromatography with electro chemical detector (ECD-HPLC).
The mitogenic activities of splenic lymphocytes were measured by
using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide
(MTS) assay and alkaline phosphatase (ALP) assay. Furthermore, the
effects of needle stimulation on learning and memory ability were
studied by the step-through type passive avoidance test. Norepinephrine
and dopamine contents in the frontoparietal cerebral cortex, ventral
hippocampus and olfactory bulb were decreased in the OVX group,
and both MTS activity and ALP activity were decreased 20 days after
ovariectomy. The mean latent period was also shortened in the passive
avoidance test in the OVX group. However, applying needle stimulation
increased norepinephrine and dopamine contents in the brain regions,
and enhanced mitogenic activities of splenic lymphocytes. The stimulation
also improved memory-related behavior. It was concluded from this
study that after mice were stimulated by subcutaneous needle insertion,
overall changes were observed in central nervous system (including
retention of memory) and immune functions. The study suggests that
acupuncture improves the memory loss and decrease of immune responses
accompanying aging and/or menopause, and the that it may have an
important role in medical care for the elderly."
Zhao
H, Tian ZZ, Chen BY. An important role of corticotropin-releasing
hormone in electroacupuncture normalizing the subnormal function
of hypothalamus-pituitary-ovary axis in ovariectomized rats.
Neurosci Lett 2003 Sep 25;349(1):25-8. In the present study, the
effects of electroacupuncture (EA) at a group of specific acupoints
on corticotropin-releasing hormone (CRH) and gonadotropin-releasing
hormone (GnRH) immunoreactivity (ir) in the hypothalamuses of ovariectomized
rats were observed. Meanwhile the blood E2 level was detected. The
results showed that EA might significantly increase the blood level
of E2 and GnRH cell number in the ovariectomized rats. The number
of CRH neurons was higher in the group ovariectomized with EA than
that in the ovariectomized and intact groups. Interestingly enough,
only in the group ovariectomized with EA was observed the co-localization
of CRH-ir and GnRH-ir substances in one cell of hypothalamic nucleus
paraventricularis by immunofluorescent double-labeling histochemistry
combining laser con-focal scanning microscope. The results suggest
that CRH might be an important factor in EA normalizing the subnormal
function of hypothalamus-pituitary-ovary axis.
Wu L, Zhou X. 300
cases of menopausal syndrome treated by acupuncture. J
Tradit Chin Med. 1998 Dec;18(4):259-62.
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