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Stroke (apoplexy) is one of the neurological disorders most commonly
seen in Chinese acupuncture clinics. Besides the large number of
studies that have been published in China, several studies have
been done in the West as well. In one Swedish study, stroke patients
receiving acupuncture recovered both faster and to a greater extent
than did the control group and had significant differences in improvement
of balance, mobility, activities of daily living, quality of life
and admission times in hospital/nursing homes (Johansson et al 1993).
Other studies have shown significantly greater improvement in acupuncture
groups than in control groups (Tidsskr et al 1998, Kjendahl et al
1997, Wong et al 1999, Zhou et al 1997, Chen et al 1990, Pei et
al 2001, Li et al 1989). Several Chinese studies have reported that
AP treatment of post-stroke aphasia (loss of the ability to use
or comprehend language) yields superior results in comparison to
control groups.
Mechanisms which may
explain spontaneous recovery following a stroke include the resolution
of swelling (edema) and the recovery of brain tissue that was injured
but not destroyed. Research suggests that acupuncture treatment
may help facilitate both of these processes by improving blood circulation
to the brain. In examining stroke patients before and after undergoing
acupuncture treatment, Chinese researchers have observed positive
changes in several different physiological indicators. These include
EEG, hemorheology, and blood serum levels of lipoproteins. Acupuncture
treatment has been found to improve blood circulation to the brain
and increase the partial pressure of oxygen and the supply of nutrients
to undestroyed brain cells surrounding the area damaged by a stroke.
Depressed stroke victims are less likely to recover, and any enhancing
effects of acupuncture on mental well-being should be considered,
in addition to acupuncture’s effects on blood flow to the
brain.
Whereas studies from
China and Japan heavily support a role for acupuncture treatment
in thousands of cases of stroke, Western studies are often equivocal.
Why is this so? First, the acupuncture approach is different. In
the Orient, acupuncture is done daily to twice daily for maximum
stimulation of the nervous system. Various experts recommend treating
3 times weekly as a minimum; more would be better. Second, Western
studies use standard points on the arms and legs. Chinese studies
indicate that using scalp points alone or in addition to provide
a stronger input. A newer approach, Xingnao Kaiqiao (“consciousness
awakening"), generated by Dr. Shi Xuemen and co workers (Shi
et al 1989), appears extremely attractive. They treat a number of
traditional points on the body in sequence each to the point of
muscle jerking. In a series of 3200 patients, an essential cure
is claimed in 58% and 90% effective improvement to the point of
reasonable self sufficiency.
Johansson B B 1993 Has sensory stimulation a role in stroke
rehabilitation? Scandinavian Journal of Rehabilitation.
RESULTS: “Patients receiving acupuncture recovered faster
and to a greater degree than those in the control group. There was
a significant between-group difference in balance, mobility, activities
of daily living on Barthel's Index, quality of life on the Nottingham
Health Profile, and number of days spent in hospitals or nursing
homes.” CONCLUSIONS: “Treatment with acupuncture in
patients with stroke who have severe impairment can achieve functional
outcomes better than those achieved with contemporary physiotherapy.”
Ou,Y.W., Han,L., Da,C.D.,
Huang, Y.L., Cheng, Y.S. Influence of acupuncture upon expressing
levels of basic fibroblast growth factor in rat brain following
focal cerebral ischemia - evaluated by time-resolved fluorescence
immunoassay. Neurol Res Vol.23(1) p.47-50. 2001. RESULTS:
“Electroacupuncture (EA) alleviated the infarction and swelling
induced by the ischemia, and markedly enhanced the opening amount
of the micrangium. There also appeared to be a slight increase in
cortical total protein in the EA group. EA substantially up regulated
the level of basic fibroblastic growth factor (bFGF), especially
in the frontoparietal cortex (but also the striatum), as compared
to the ischemia alone group of rats.” AUTHOR'S CONCLUSIONS:
“Laboratory support exists for a potential neuroprotective
mechanism of EA via endogenous bFGF expression, providing the possibility
of combining the use of acupuncture and bFGF in the treatment of
acute cerebral ischemic injury.”
Tidsskr Nor Laegeforen
1998 Mar 30;118(9):1362-6 Acupuncture in stroke. Kjendahl
A, Sallstrom S, Osten PE, Stanghelle JK, Borchgrevink CF.Sunnaas
sykehus, Nesoddtangen. CONCLUSIONS: “The results show that
there was a significantly greater improvement in the acupuncture
group than in the control group, both during the six- week treatment
period, and even more so during the following year. These assessments
were based on the Motor Assessment Scale, the Sunnaas Index of Daily
Living (ADL), the Nottingham Health Profile and the patients' social
circumstances.”
Kjendahl A, Sallstrom
S, Osten PE, Stanghelle JK, Borchgrevink CF. A one year
follow-up study on the effects of acupuncture in the treatment of
stroke patients in the subacute stage: a randomized, controlled
study. Clin Rehabil 1997 Aug;11(3):192-200. RESULTS: The
results show that the acupuncture group improved significantly more
than the controls, both during the treatment period of six weeks,
and even more during the following year, both according to MAS,
ADL, NHP and the social situation. CONCLUSION: Although the mechanism
of the effects is debatable, there seems to be a positive long-term
effect of acupuncture given in the subacute stage post stroke.
Wong AM, Su TY, Tang
FT, Cheng PT, Liaw MY 1999. Clinical trial of electrical
acupuncture on hemiplegic stroke patients. Am J Phys Med
Rehabil 1999 Mar-Apr;78(2):117-22. RESULTS: “Patients treated
with electrical acupuncture had a shorter duration of hospital stay
for rehabilitation and better neurological and functional outcomes
than the control group had, with a significant difference in scores
for self-care and locomotion (P = 0.02).”
Zhou J, Zhang F.
A research on scalp acupuncture for cerebral infarction.
J Tradit Chin Med 1997 Sep;17(3):194-7. CONCLUSIONS: “After
treatment, such symptoms as hemiplegia, lingual dysfunction, facial
and tongue paralysis, and the laboratory indexes of blood fat, fibrinogen
and hemorrheology were obviously improved (P < 0.01 or 0.05).
The therapeutic effect of scalp acupuncture was obviously better
than that of Western medicine (P < 0.01).”
Chen DZ. Evaluation
of therapeutic effects of acupuncture in treating ischemic cerebrovascular
disease. Zhong Xi Yi Jie He Za Zhi 1990 Sep;10(9):526-8,
515. RESULTS: “After treatment the results were as follows:
the marks of functional nervous damage in the test group were reduced
13.0 average, but only 3.75 in the control group. There was a very
remarkable difference between these two groups (P less than 0.001).
Slow wave of the EEG-map in the test group were reduced 1.70 level
average, but only 0.05 in the control group (P less than 0.001).
theta wave of the EEG-map in the test group were reduced 1.05 level
average, but only 0.25 level in the control group (P less than 0.001).
The diversity of latent period of P45 peak wave value between left
limbs and right limbs were reduced evidently in the test group and
showed a very significant statistical difference. (P less than 0.05)
as compared with the control group.”
Pei J, Sun L, Chen R,
Zhu T, Qian Y, Yuan D. The effect of electro-acupuncture
on motor function recovery in patients with acute cerebral infarction:
a randomly controlled trial. J Tradit Chin Med 2001 Dec;21(4):270-2.
Randomized 86 patients into acupuncture and non-acupuncture groups.
CONCLUSION: “Early acupuncture treatment for acute stroke
patients may improve motor functions, and consequently the activities
of daily living.”
Shi et al 1989.
Clinical research on 50 cases of stable stage apoplexy treated by
acupuncture using brain activating and consciousness regaining principles.
Zhong Xi Yi Jie He Za Zhi 1989 Nov;9(11):653-5, 643-4 . CONCLUSIONS:
“The experimental research also indicated that this therapeutic
method could improve blood rheology, microcirculation, increase
the content of HDL and resist thrombosis. Thus, it could promote
the injured cerebral cells to be recovered.”
Zhai N, Lu X, Shi X,
Xu P. 1993. Morphological study on acupuncture in interfering
experimental cerebral infarction in rats. II. Change of ischemic
area in cerebral interior. Zhen Ci Yan Jiu 1993;18(3):209-12.
RESULTS: “Whereas the ischemic area in the cortex disappeared
in the acupuncture group, the ischemic volume reduced to 6.3 percent
of the whole. The experiment pointed out that the acupuncture is
an effective therapeutic procedure for cerebral infarction.”
Yu YH, Wang HC, Wang
ZJ. The effect of acupuncture on spinal motor neuron excitability
in stroke patients. Zhonghua Yi Xue Za Zhi (Taipei) 1995
Oct;56(4):258-63. CONCLUSIONS: “This result provides positive
evidence of increased spinal motor neuron excitability in paretic
limbs of stroke patients and also of the acupuncture effect which
decreased that excitability.”
Yuan X, Hao X, Lai Z,
Zhao H, Liu W. Effects of acupuncture at fengchi point (GB
20) on cerebral blood flow. J Tradit Chin Med 1998 Jun;18(2):102-5.
RESULTS: “Blood velocity in the vertebral artery and the basilar
artery was observed before and after acupuncture at Fengchi point
(GB 20) in 97 patients by transcranial Doppler ultrasonic detecting.
The results showed that the blood velocity in patients with either
high or low blood flow had significant changes after acupuncture
(P < 0.001).”
Li J. Forty-five
cases of apoplexy treated by electroacupuncture at the points of
yin meridians. J Tradit Chin Med 2001 Mar;21(1):20-2.
Lee
JD, Chon JS, Jeong HK, Kim HJ, Yun M, Kim DY, Kim DI, Park CI, Yoo
HS. The cerebrovascular response to traditional acupuncture
after stroke. Neuroradiology 2003 Aug 27;. "We obtained
single-photon emission computed tomography (SPECT) brain perfusion
images of six patients with middle cerebral artery occlusion obtained
before and after acupuncture and compared the changes in regional
cerebral blood flow (rCBF) to those in normal control. Images were
obtained before and after acupuncture at six traditional acupoints
(LI 4, 10, 11, 15 and 16 and TE5) in the affected arm. The baseline
image was subtracted from the postacupuncture image, to produce
a subtraction image displaying only voxels with values >2 SD
from the mean and those voxels were coregistered to the baseline
SPECT or T2-weighted MRI. Similar images were obtained before and
after acupuncture of eight normal volunteers. Statistical parametric
mapping with a threshold of P =0.001 and a corrected P of 0.05 was
performed for group comparison between postacupuncture and baseline
SPECT. Focally increased CBF was seen in all patients especially
in the hypoperfused zone surrounding the ischaemic lesion, the ipsilateral
or contralateral sensorimotor area, or both. Normal subjects showed
increased rCBF mainly in the parahippocampal gyrus, premotor area,
frontal and temporal areas bilaterally and ipsilateral globus pallidus.
Acupuncture stimulation after stroke patients appears to activate
perilesional or use-dependent reorganised sites and might be a way
of looking at brain reorganisation."
Moon
SK, Whang YK, Park SU, Ko CN, Kim YS, Bae HS, Cho KH Antispastic
effect of electroacupuncture and moxibustion in stroke patients.
Am J Chin Med 2003;31(3):467-74. "Spasticity is a
frequently observed motor impairment that develops after stroke.
The objective of this study was to evaluate the efficacy of electroacupuncture
(EA) and moxibustion (Mox) on spasticity due to stroke. The subjects
consisted of 35 stroke patients with elbow spasticity whose mean
duration of stroke was 2.97 months. Fifteen patients were randomized
to the EA group, ten to Mox, and ten to control. Every other day,
30 minutes of electrical stimulation with a frequency of 50 Hz was
given through four needles on the Ch'u-Ch'ih-San-Li (LI-11-LI-10)
and Wai-Kuan-Ho-Ku (TB-5-LI-4) points of the paretic side. Direct
Mox was applied to Ch'u-Ch'ih (LI-11), San-Li (LI-10), Wai-Kuan
(TB-5) and Ho-Ku (LI-4) points three times a day every other day.
The control group was given only the routine acupuncture therapy
for stroke and range of motion (ROM) exercise, which were also applied
to the EA and Mox groups. The efficacy of treatment was measured
before, immediately, 1 hour, 3 hours, 1 day, 5 days, 10 days and
15 days after the start of treatment using a modified Ashworth scale
(MAS). In the EA group, spasticity was significantly reduced immediately,
1 hour and 3 hours after treatment (p < 0.05). Reductions were
significant on the 5th day and thereafter (p < 0.05). In the
Mox group, there was no significant change in the MAS scores after
the first treatment. In the Mox and control group, there was no
significant change in MAS scores. This study suggests that EA can
temporarily reduce spasticity due to stroke, and if applied repeatedly
it can maintain reduced spasticity."
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