There are similarities between the neurophysiology of itch and pain. Both sensations depend on stimulation of C fibers (e.g. by histamine or prostaglandins). Precisely whether this is felt as itch or pain does not seem to depend on the intensity of stimulation, and so it is possible that there are different populations of C fibers serving each sensation (Lundeberg et al 1987). As is the case with pain, acupuncture stimulation can reduce itch. There have been several studies of the effect of acupuncture on experimental itch induced by intradermal injection of histamine. The mean duration and intensity of itch may be reduced significantly by acupuncture. Acupuncture may also reduce maximal flare area (Solomon & Lichter 1984).

Lundeberg T, Bondesson L, Thomas M 1987. Effect of acupuncture on experimentally induced itch. British Journal of Dermatology 117:771-777.

Solomon L M, Lichter E A 1984 Effect of acupuncture on experimentally induced itch. Acta Dermatologica Venereologica (Stockholm) 64:129-133.

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